中文簡介

關(guān)于雜志ACS傳染病是第一本強調(diào)化學(xué)及其在傳染病研究的多學(xué)科和協(xié)作領(lǐng)域中的作用的雜志。該雜志的范圍包括與傳染病研究有關(guān)的化學(xué)的所有方面，包括對病原體的研究、宿主與病原體的相互作用、治療學(xué)、診斷學(xué)、疫苗、藥物輸送系統(tǒng)以及與傳染病有關(guān)的其他生物醫(yī)學(xué)技術(shù)的發(fā)展。編輯們精通傳染病的化學(xué)和生物學(xué)，該雜志旨在彌合這兩門學(xué)科之間的鴻溝。ACS傳染病歡迎提交化學(xué)和生物學(xué)平衡的文章，并鼓勵圍繞特定病原體和疾病相關(guān)問題進行討論。期刊范圍該期刊涵蓋的主題包括但不限于以下內(nèi)容:病原體與宿主-病原體相互作用運用結(jié)構(gòu)生物學(xué)、化學(xué)生物學(xué)、糖生物學(xué)、物理化學(xué)、核酸化學(xué)、生物化學(xué)等，闡明發(fā)病的分子機制發(fā)展工具解剖發(fā)病機制治療利用目標(biāo)、表型或基于計算的方法發(fā)現(xiàn)和開發(fā)治療傳染病的新制劑，重點是建立作用機制、理解結(jié)合模式和抑制機制，以及/或討論藥物開發(fā)面臨的病原體特異性挑戰(zhàn)開發(fā)新技術(shù)，以促進對潛在藥物靶點的鑒定、驗證和優(yōu)先排序，或評估抗感染藥物的細胞滲透的物理化學(xué)基礎(chǔ)抗菌素耐藥性的機制研究疫苗合成疫苗和小分子疫苗佐劑的發(fā)現(xiàn)和開發(fā)表位結(jié)合的結(jié)構(gòu)、物理或計算研究診斷利用物理、表面、分析和納米化學(xué)技術(shù)開發(fā)新的和改進的診斷方法利用結(jié)構(gòu)生物學(xué)、分子生物學(xué)和化學(xué)生物學(xué)研究診斷目標(biāo)藥物輸送系統(tǒng)利用新材料和新技術(shù)，如納米技術(shù)，來運送抗菌藥物

　　英文簡介

About the JournalACS Infectious Diseases is the first journal to highlight chemistry and its role in the multidisciplinary and collaborative field of infectious disease research. The scope of the journal encompasses all aspects of chemistry relating to infectious diseases research including research on pathogens, host-pathogen interactions, therapeutics, diagnostics, vaccines, drug-delivery systems, and other biomedical technology development pertaining to infectious diseases.With editors well-versed in both chemistry and the biology of infectious diseases, the journal aims to bridge the gap between these two disciplines. ACS Infectious Diseases welcomes submission of articles with a balance of chemistry and biology, and encourages discussions centered on specific pathogen- and disease-related issues.Journal ScopeTopics covered by the journal include but are not limited to the following:Pathogens and Host-Pathogen InteractionsUse of structural biology, chemical biology, glycobiology, physical chemistry, nucleic acid chemistry, and biochemistry to elucidate molecular mechanisms of pathogenesisDevelopment of tools to dissect mechanisms of pathogenesisTherapeuticsUse of target-, phenotypic-, or computational-based approaches for discovery and development of new agents to treat infectious diseases, with an emphasis on establishing mechanism of action, understanding binding mode and inhibitory mechanism, and/or discussing pathogen-specific challenges to drug developmentDevelopment of new technologies to facilitate characterization, validation, and prioritization of potential drug targets or to assess the physicochemical bases for cellular penetration of anti-infectivesMechanistic investigations of antimicrobial resistanceVaccinesDiscovery and development of synthetic vaccines and small molecule vaccine adjuvantsStructural, physical, or computational investigations of epitope bindingDiagnosticsDevelopment of novel and improved diagnostics using physical, surface, analytical, and nano chemistry techniquesUse of structural biology, molecular biology, and chemical biology to investigate diagnostics targetsDrug Delivery SystemsUse of novel materials and technologies, such as nanotechnologies, for delivery of antimicrobial agents

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