中文簡介

對生物樣品中的外源生物和生物制劑進行選擇性、敏感性和可重復性分析，從而獲得可靠的數據，這是每一個成功的藥物開發項目的基礎和關鍵部分。同樣的原則也可以應用于許多其他領域的研究，如法醫學、毒理學和體育興奮劑檢測。《生物分析》領域結合了復雜的技術，將樣品制備和先進的分離技術與MS和NMR檢測系統、自動化和機器人技術相結合。監管機構制定的有關方法開發和驗證的標準越來越多地界定了速度和質量之間的界限。《生物分析》是一門進步的學科，未來將有許多令人興奮的機會進一步減少樣本量、分析成本和環境影響，以及提高靈敏度、特異性、準確性、效率、分析吞吐量、數據質量、數據處理和處理。《生物分析》雜志側重于檢測或定量研究人類或動物生物樣品中分析物的技術和方法。生物分析鼓勵提交描述前瞻性應用的文章，包括生物傳感器、微流體、微型化分析設備和新的連字符和多維技術。生物分析以簡潔、一目了然的文章格式提供基本信息。該領域的關鍵進展由國際專家進行報告和分析，為現代生物分析學家提供了一個權威而又容易接近的論壇。主要的主題包括：分析物提取和樣品制備，包括微取樣色譜與分離科學MS、NMR等關鍵檢測方法，包括配體結合檢測藥物和代謝物分析生物標志物檢測、診斷檢測和檢測試劑盒方法開發和驗證方法創新的生物分析方法和新的儀器設備實驗室自動化及效率規管及遵從問題數據處理及管理

　　英文簡介

Reliable data obtained from selective, sensitive and reproducible analysis of xenobiotics and biotics in biological samples is a fundamental and crucial part of every successful drug development program. The same principles can also apply to many other areas of research such as forensic science, toxicology and sports doping testing.The bioanalytical field incorporates sophisticated techniques linking sample preparation and advanced separations with MS and NMR detection systems, automation and robotics. Standards set by regulatory bodies regarding method development and validation increasingly define the boundaries between speed and quality.Bioanalysis is a progressive discipline for which the future holds many exciting opportunities to further reduce sample volumes, analysis cost and environmental impact, as well as to improve sensitivity, specificity, accuracy, efficiency, assay throughput, data quality, data handling and processing. The journal Bioanalysis focuses on the techniques and methods used for the detection or quantitative study of analytes in human or animal biological samples. Bioanalysis encourages the submission of articles describing forward-looking applications, including biosensors, microfluidics, miniaturized analytical devices, and new hyphenated and multi-dimensional techniques.Bioanalysis delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for the modern bioanalyst.Principal themes include:Analyte extraction and sample preparation, including microsamplingChromatography and separation sciencesMS, NMR and other key detection methods, including ligand binding assaysDrug and metabolite assaysBiomarker assays, diagnostic assays and test kitsMethod development and validation approachesInnovative bioanalytical methods and new instrumentation and equipmentLaboratory automation and efficiencyRegulatory and compliance issuesData processing and management

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