中文簡介

概述老化細(xì)胞的目標(biāo)是發(fā)表高質(zhì)量的，創(chuàng)新的研究解決衰老生物學(xué)的基本問題。為了在《衰老細(xì)胞》雜志上發(fā)表，這項工作必須為理解衰老做出重大的新貢獻(xiàn)，并引起社會的普遍興趣。《衰老細(xì)胞》試圖涵蓋老年科學(xué)的所有領(lǐng)域，強調(diào)揭示衰老過程的機械方面的研究，以及衰老與年齡相關(guān)疾病之間的聯(lián)系。將考慮對沒有實質(zhì)力學(xué)見解的新老化過程的觀察，但對該領(lǐng)域應(yīng)具有特別高的影響。主題包括但不限于，營養(yǎng)反應(yīng)信號通路，神經(jīng)和內(nèi)分泌信號通路，組織相互作用，遺傳和表觀遺傳調(diào)控和完整性，蛋白質(zhì)平衡，晝夜節(jié)律，活性氧和線粒體，細(xì)胞衰老，干細(xì)胞，progerias和干預(yù)，影響老化是鼓勵。所有的實驗方法，包括植物模型，都是受歡迎的。關(guān)注特定年齡相關(guān)病理的發(fā)病機制的論文也很有趣，但應(yīng)該對衰老和疾病之間的基本聯(lián)系提供新的見解。目標(biāo)和范圍衰老細(xì)胞覆蓋:遺傳學(xué)和功能基因組學(xué):影響壽命的突變;基因的同源性;機體和細(xì)胞老化;基因操作。信號和基因表達(dá):與年齡相關(guān)的變化與表型和生理聯(lián)系的機制;胞內(nèi)信號;細(xì)胞與組織的相互作用;激素、免疫和炎癥系統(tǒng)。細(xì)胞增殖、衰老與死亡:復(fù)制性衰老;細(xì)胞凋亡;端粒生物學(xué)等內(nèi)外因素的影響;時間細(xì)胞老化;老化細(xì)胞的表型。細(xì)胞應(yīng)激和損傷:自由基對細(xì)胞和組織的外在和內(nèi)在影響;自由基防御與損傷;自由基作為信號分子;壓力和衰老。干細(xì)胞與衰老:年齡對干細(xì)胞生成的影響遷移和體內(nèi)平衡;莖cell-niche交互;監(jiān)管機制。綜合生理學(xué):機體、細(xì)胞和分子水平衰老過程的結(jié)果。生物人口學(xué)與比較研究:人口與跨物種比較研究。老年與長壽新理論:在已建立和新穎的老年與長壽理論的最廣泛層面上的討論。《衰老細(xì)胞》創(chuàng)刊于2002年，雙月刊。文章類型包括:新穎的，同行評審的研究，集中在上述領(lǐng)域。對近期備受矚目的研究進(jìn)行評估。評注對期刊或其他主要期刊上當(dāng)前特別重要的論文進(jìn)行評價的評注。生物老化一般理論的發(fā)展與批判。關(guān)鍵字衰老，衰老，長壽，壽命，細(xì)胞衰老，細(xì)胞死亡，細(xì)胞凋亡，壓力，自由基，端粒酶，端粒，老年學(xué)，老年醫(yī)學(xué)抽象和索引信息學(xué)術(shù)檢索(EBSCO出版)學(xué)術(shù)搜索校友版(EBSCO出版)學(xué)術(shù)搜尋總理(EBSCO出版)CAS:化學(xué)文摘服務(wù)(ACS)CSA生物科學(xué)數(shù)據(jù)庫(ProQuest)Embase(愛思唯爾)InfoTrac(蓋爾Cengage)Ingenta選擇ISI提醒服務(wù)期刊引用報告/科學(xué)版(Clarivate Analytics)MEDLINE / PubMed(NLM)神經(jīng)科學(xué)抽象(它)ProQuest生物科學(xué)收藏(ProQuest)PubMed膳食補充劑子集(NLM)科學(xué)引文索引擴展(Clarivate Analytics)

　　英文簡介

OverviewThe aim of Aging Cell is to publish the highest quality, innovative research addressing fundamental issues in the biology of aging. For publication in Aging Cell, the work must provide a major new contribution to the understanding of aging and be of general interest to the community. Aging Cell seeks to cover all areas of geroscience, highlighting research that uncovers mechanistic aspects of the aging process, as well as the links between aging and age-related disease. Observations of novel aging processes without substantial mechanistic insight will be considered, but should be of especially high impact for the field. Topics including, but not limited to, nutrient-responsive signaling pathways, neuronal and endocrine signaling pathways, tissue interactions, genetic and epigenetic regulation and integrity, proteostasis, circadian rhythms, ROS and mitochondria, cellular senescence, stem cells, progerias and interventions that affect aging are encouraged. All experimental approaches, including plant models, are welcome. Papers that focus on the pathogenesis of a specific age-related pathology are also of interest, but should offer new insights into the fundamental links between aging and disease.Aims and ScopeAging Cell covers:Genetics and functional genomics: mutations affecting longevity; gene homologies; organismal and cellular aging; gene manipulation.Signaling and gene expression: mechanisms linking age-associated changes with phenotypes and physiology; intracellular signaling; interactions between cells and tissues; hormonal, immune, and inflammatory systems.Cell proliferation, aging and death: replicative senescence; apoptosis; telomere biology and other intrinsic and extrinsic influences; chronological cellular aging; phenotypes of aging cells.Cell stress and damage: extrinsic and intrinsic influences of free radicals on cells and tissues; free radical defense and damage; free radicals as signaling molecules; stress and aging.Stem cells and aging: effects of age on stem cell generation; migration and homeostasis; stem cell-niche interactions; regulatory mechanisms.Integrative physiology: outcomes of aging processes at organismal, cellular and molecular levels.Biodemography and comparative studies: population and cross-species comparative studies.New theories of aging and longevity: discussion at the broadest level of established and novel theories of aging and longevity.Aging Cell was launched in 2002 and is published bimonthly. Article types include:Novel, peer-reviewed research, concentrating in the areas described above.Reviews and minireviews assessing high-profile recent research.Commentaries evaluating especially important current papers in the Journal or other leading journals.Development and criticism of general theories of biological aging.KeywordsAging, ageing, longevity, lifespan, cell senescence, cell death, apoptosis, stress, free radicals, telomerase, telomeres, gerontology, geriatric Abstracting and Indexing InformationAcademic Search (EBSCO Publishing)Academic Search Alumni Edition (EBSCO Publishing)Academic Search Premier (EBSCO Publishing)CAS: Chemical Abstracts Service (ACS)CSA Biological Sciences Database (ProQuest)Embase (Elsevier)InfoTrac (GALE Cengage)Ingenta SelectISI Alerting ServicesJournal Citation Reports/Science Edition (Clarivate Analytics)MEDLINE/PubMed (NLM)Neurosciences Abstracts (ProQuest)ProQuest Biological Science Collection (ProQuest)PubMed Dietary Supplement Subset (NLM)Science Citation Index Expanded (Clarivate Analytics)

　　近年期刊自引率趨勢圖

　　JCR分區(qū)

JCR分區(qū)等級	JCR所屬學(xué)科	分區(qū)	影響因子
Q1	CELL BIOLOGY	Q1	11.005
	GERIATRICS & GERONTOLOGY	Q1

　　近年期刊影響因子趨勢圖

　　CiteScore數(shù)值

CiteScore	SJR	SNIP	學(xué)科類別	分區(qū)	排名	百分位
13.80	2.751	1.770	大類：Biochemistry, Genetics and Molecular Biology 小類：Aging	Q1	2 / 36	95%
			大類：Biochemistry, Genetics and Molecular Biology 小類：Cell Biology	Q1	32 / 274	88%